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“Isagenix isn’t something that I or most registered dietitians I know would ever recommend,” says Maddie Pasquariello, a registered dietitian in Brooklyn, New York. For instance, she says that the 30-day Reset’s use of cleanse days could potentially encourage unhealthy or disordered eating habits rather than supporting long-term lifestyle changes. “If your internal organs are in working order, you don’t need a detox or cleanse to support your health goals,” she explains.
While Pasquariello notes that the IsaLean shake appears to have adequate nutrition and would likely provide some micronutrient benefits, it also contains sugar and other additives, such as flavorings. Additionally, Pasquariello points out that a single serving of the shake contains more than 50% of the recommended daily value for some nutrients, such as vitamin B6, B12 and manganese, which may be of concern since the 30-Day Reset recommends drinking multiple servings on shake days.
“It doesn’t appear that any of the micronutrient quantities listed would verge into toxic levels, even if you did drink more than one shake per day, but it’s something to consider,” she says.
A Look At Isagenix’s Cited Research
Isagenix has a small body of research on its website supporting certain claims for its products.
For example, one very small 2022 study divided 20 participants with overweight or obesity into two groups. One group fasted one day per week, the other two days per week. On fast days, both groups consumed around 400 calories. On food days, participants consumed a diet of 1,500 calories for women and 1,850 calories for men. Both groups consumed Isagenix products and whole foods to meet their daily caloric and nutrition requirements. After a four-week period, both groups experienced lower body weights, body fat percentages and blood sugar levels. But the two fast day per-week group lost slightly more weight overall.
“The study findings suggest that, if anything, results are largely attributed to various intermittent fasting protocols or caloric restriction,” Pasquellario explains. “Even if you are practicing intermittent fasting under the supervision of an RD and medical team, you don’t need this product lineup to do so.”
What’s more, Pasquariello notes that some of the studies listed on Isagenix’s website (such as the one featured above) have small sample sizes and at least one conflict of interest. For instance, they are either funded directly by Isagenix or conducted by professionals who work as consultants with Isagenix. “This isn’t what I hope to see if I’m seeking gold-standard research about a particular nutrient or ingredient,” explains Pasquariello.
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